MATRIXYL 10 MG

Matrixyl belongs to a class of ingredients called matrikines—extracellular matrix-derived peptides that regulate cell activity.

1. Scientific Classification & Mechanism

Matrixyl belongs to a class of ingredients called matrikines—extracellular matrix-derived peptides that regulate cell activity.

Instead of exfoliating or artificially filling the skin, Matrixyl acts as a cellular messenger. When natural collagen breaks down from aging or UV damage, it fragments into peptides. The skin detects these fragments as a signal that it is damaged and needs repair. Matrixyl mimics these natural fragments, "tricking" the skin into thinking it needs to produce fresh structural proteins.

2. The Matrixyl Evolution (Key Variants)

Sederma (the French laboratory that created Matrixyl) has developed several generations of this peptide:

Matrixyl (Original)

• INCI Name: Palmitoyl Pentapeptide-4

• Structure: 5 amino acids linked to a palmitic fatty acid.

• Function: Stimulates Collagen Type I, III, and IV.

Matrixyl 3000

• INCI Name: Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7

• Structure: A synergistic blend of two distinct peptides.

• Function: Reduces chronic low-grade inflammation (inflammaging) and doubles collagen production.

Matrixyl Synthe'6

• INCI Name: Palmitoyl Tripeptide-38

• Structure: 3 amino acids.

• Function: Rebuilds the skin matrix by stimulating 6 major constituents: Collagen I, III, IV, Fibronectin, Hyaluronic Acid, and Laminin-5.

Note: The Palmitic Acid attached to these peptides is crucial. Peptides are water-soluble and normally cannot cross the skin's fatty lipid barrier. The palmitic fatty acid group acts as a delivery vehicle, allowing the peptide to penetrate the epidermis.

3. Advanced Formulation Rules

For cosmetic chemistry or product formulation:

• pH Stability: Matrixyl requires a pH range of 4.5 to 6.5.

• Incompatibilities: It should not be formulated in highly acidic environments (pH < 4.0). Direct acids like Glycolic or Salicylic Acid can break the peptide bonds via hydrolysis, rendering the ingredient completely useless.

• Copper Peptide Clash: Avoid mixing Matrixyl in formulas containing pure Copper Peptides, as they can compete for the same cellular receptors and neutralize each other.

4. Clinical Efficacy Data

Benchmarks from Sederma's clinical trials:

• Wrinkle Depth: Matrixyl 3000 at a 3% concentration demonstrated a substantive reduction of deep wrinkles by up to 45% over a 2-month study.

• Skin Roughness: Clinical profiling showed a 21% reduction in overall skin roughness, signaling significant tissue remodeling.

Product Details

• Compound: MATRIXYL
• Quantity: 10 mg
• Form: Lyophilized Powder
• Purity: ≥99% (if applicable)
• Storage: Store in a controlled laboratory environment, protected from light and moisture

Research Use Only

This product is intended strictly for laboratory research use only.
Not for human consumption.
Not for medical use.
Not intended to diagnose, treat, cure, or prevent any disease.
Not approved by the FDA.

This product is in powder form and is not reconstituted. All materials sold on this site are for laboratory research purposes only and are subject to our Terms and Conditions.

By purchasing, the buyer confirms this product will be used strictly for laboratory research purposes.